Modelling the Toxicity of Nanoparticles

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Tran, Lang (Επιμελητής έκδοσης), Bañares, Miguel A. (Επιμελητής έκδοσης), Rallo, Robert (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2017.
• Σειρά: Advances in Experimental Medicine and Biology, 947
• Θέματα: Medicine.; Pharmacology.; Systems biology.; Nanotechnology.; Biomedicine.; Pharmacology/Toxicology.; Systems Biology.

In today’s nanotechnology and pharmaceutical research, alternative toxicology testing methods are crucial for ethically and commercially sound practice. This book provides practical guidelines on how to develop and validate quantitative nanostructure-toxicity relationship (QNTR) models, which are id...

Πίνακας περιεχομένων:

• Engineered Nanoparticles – Their physico-chemical characteristics and how to measure them
• Measurement
• The Life-Cycle of Engineered Nanoparticles
• From Dose to Response – In vivo Nanoparticle Processing and Potential Toxicity
• From Dose to Response – Literature review od (Q)SAR Modelling of Nanomaterial Toxicity
• Systems biology to support nanomaterial grouping
• Multiscale modelling of bionano interface
• Biological Surface Adsorption Index of Nanomaterials - Modeling Surface Interactions of Nanomaterials with Biomolecules
• Case study I - An integrated data-driven strategy for safe-by-design nanoparticles: The FP7 MODERN Project
• Case study II - Compilation of Data and Modeling of Nanoparticle Interactions and Toxicity and in the European NanoPUZZLES Project
• Case study III – The construction of a nanotoxicity database: the MOD-ENP-TOX experience.