How to Overcome the Antibiotic Crisis Facts, Challenges, Technologies and Future Perspectives /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Stadler, Marc (Επιμελητής έκδοσης), Dersch, Petra (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Έκδοση: 1st ed. 2016.
• Σειρά: Current Topics in Microbiology and Immunology, 398
• Θέματα: Medicine.; Medical microbiology.; Pharmacology.; Medicinal chemistry.; Infectious diseases.; Bacteriology.; Biomedicine.; Medical Microbiology.; Infectious Diseases.; Pharmacology/Toxicology.; Medicinal Chemistry.; Veterinary Medicine/Veterinary Science.

This volume focuses on antibiotics research, a field of topical significance for human health due to the worrying increase of nosocomial infections caused by multi-resistant bacteria. It covers several basic aspects, such as the evolution of antibiotic resistance and the influence of antibiotics on...

Πίνακας περιεχομένων:

• Tackling threats and future problems of multidrug-resistant bacteria.-Emergence and spread of antimicrobial resistance: recent insights from bacterial population genomics
• Epidemiology of Staphylococcus aureus nasal carriage patterns in the community
• Diagnostics and resistance profiling of bacterial pathogens
• Use of antibiotics and antimicrobial resistance in veterinary medicine as exemplified by the swine pathogen Streptococcus suis.-Antibiotics and the intestinal microbiome: individual responses, resilience of the ecosystem and the susceptibility to infections
• Anti-virulence strategies to target bacterial infections
• Strategies to block bacterial pathogenesis by interference with motility and chemotaxis
• New horizons in the development of novel needle-free immunization strategies to increase vaccination efficacy
• History of antibiotics research
• Actinobacteria and Myxobacteria – Two of the most important bacterial resources for novel antibiotics
• Exploitation of fungal biodiversity for discovery of novel antibiotics
• Strategies for the discovery and development of new antibiotics from natural products: Three Case Studies
• New structural templates for clinically validated and novel targets in antimicrobial drug research and development
• Synthesis of antibiotics
• Antibiotics clinical development and pipeline
• Anti-infectives in drug delivery—overcoming the Gram-negative bacterial cell envelope.