Incorporation of Heterocycles into Combinatorial Chemistry

• Main Author: Babaev, Eugene V. (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2017.
• Series: SpringerBriefs in Molecular Science,
• Subjects: Chemistry.; Pharmaceutical technology.; Organic chemistry.; Science education.; Organic Chemistry.; Pharmaceutical Sciences/Technology.; Science Education.

The author has summarized a decade of teaching combinatorial chemistry into this timely brief. The solid phase synthesis of unnatural heterocyclic alpha-amino acids is illustrated by practical examples starting from the ABCs of peptide synthesis explored in chapter one. Chapter two is concerned with...

Table of Contents:

• Introduction
• Peptide Synthesis of Libraries of Non-Natural Amino Acids
• The choice of tools for implementing multi-stage transformations. SPOS for Beginners
• Secrets of Parallel Liquid-Phase Synthesis
• Most Combinatorial LPOS Reactions: Reductive Amination with a Scavenger
• A Parallel Ugi Reaction
• Combinatorial Heterocyclic Chemistry in Higher School.