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03056nam a22004575i 4500 |
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978-3-319-50047-8 |
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DE-He213 |
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20170207130642.0 |
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cr nn 008mamaa |
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170207s2017 gw | s |||| 0|eng d |
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|a 9783319500478
|9 978-3-319-50047-8
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|a 10.1007/978-3-319-50047-8
|2 doi
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|a MMFM
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|a MED052000
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|a 616.9041
|2 23
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|a The Actin Cytoskeleton and Bacterial Infection
|h [electronic resource] /
|c edited by Hans Georg Mannherz.
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|a Cham :
|b Springer International Publishing :
|b Imprint: Springer,
|c 2017.
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|a X, 242 p.
|b online resource.
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|a text
|b txt
|2 rdacontent
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|a computer
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|2 rdamedia
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|a online resource
|b cr
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|a text file
|b PDF
|2 rda
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|a Current Topics in Microbiology and Immunology,
|x 0070-217X ;
|v 399
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|a Actin structure and dynamics -- Influence of binary actin-depolymerizing toxins on the microtubule system -- ADP-ribosylation of actin by Photorhabdus luminescens TccC3 inhibits interaction with actin binding proteins essential for treadmilling -- Pathogenic mechanisms of actin cross-linking toxins – peeling away the layers -- New concepts on bacterial effectors targeting Rho GTPases -- Interaction of bacterial ADPribosyltransferases with actin -- Yersinia's ways to activate and inactivate actin rearrangements in host cells -- The role of formins in phagocytosis of Borrelia by macrophages.
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|a This volume describes the mechanisms which bacteria have created to secure their survival, proliferation and dissemination by subverting the actin cytoskeleton of host cells. Bacteria have developed a veritable arsenal of toxins, effector proteins and virulence factors that allow them to modify the properties of the intracellular actin cytoskeleton for their own purposes. Bacterial factors either modify actin directly as the main component of this part of the cytoskeleton or functionally subvert regulatory or signalling proteins terminating at the actin cytoskeleton. In short, this volume provides an overview of the various tricks bacteria have evolved to “act on actin” in order to hijack this essential host cell component for their own needs. As such, it will be of interest to scientists from many fields, as well as clinicians whose work involves infectious diseases.
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|a Medicine.
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| 650 |
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|a Medical microbiology.
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| 650 |
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|a Pharmacology.
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|a Biomedicine.
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| 650 |
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|a Medical Microbiology.
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| 650 |
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|a Pharmacology/Toxicology.
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| 700 |
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|a Mannherz, Hans Georg.
|e editor.
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| 710 |
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|a SpringerLink (Online service)
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|t Springer eBooks
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|i Printed edition:
|z 9783319500461
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| 830 |
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|a Current Topics in Microbiology and Immunology,
|x 0070-217X ;
|v 399
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| 856 |
4 |
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|u http://dx.doi.org/10.1007/978-3-319-50047-8
|z Full Text via HEAL-Link
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| 912 |
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|a ZDB-2-SBL
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| 950 |
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|a Biomedical and Life Sciences (Springer-11642)
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