The Actin Cytoskeleton and Bacterial Infection

• Corporate Author: SpringerLink (Online service)
• Other Authors: Mannherz, Hans Georg (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2017.
• Series: Current Topics in Microbiology and Immunology, 399
• Subjects: Medicine.; Medical microbiology.; Pharmacology.; Biomedicine.; Medical Microbiology.; Pharmacology/Toxicology.

This volume describes the mechanisms which bacteria have created to secure their survival, proliferation and dissemination by subverting the actin cytoskeleton of host cells. Bacteria have developed a veritable arsenal of toxins, effector proteins and virulence factors that allow them to modify the...

Table of Contents:

• Actin structure and dynamics
• Influence of binary actin-depolymerizing toxins on the microtubule system
• ADP-ribosylation of actin by Photorhabdus luminescens TccC3 inhibits interaction with actin binding proteins essential for treadmilling
• Pathogenic mechanisms of actin cross-linking toxins – peeling away the layers
• New concepts on bacterial effectors targeting Rho GTPases
• Interaction of bacterial ADPribosyltransferases with actin
• Yersinia's ways to activate and inactivate actin rearrangements in host cells
• The role of formins in phagocytosis of Borrelia by macrophages.