Inflammation-Associated Depression: Evidence, Mechanisms and Implications

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Dantzer, Robert (Επιμελητής έκδοσης), Capuron, Lucile (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2017.
• Σειρά: Current Topics in Behavioral Neurosciences, 31
• Θέματα: Medicine.; Immunology.; Neurosciences.; Psychopharmacology.; Health psychology.; Biomedicine.; Health Psychology.

Inflammation has invaded the field of psychiatry. The finding that cytokines are elevated in various affective and psychotic disorders brings to the forefront the necessity of identifying the precise research domain criteria (RDoCs) that inflammation is responsible for. This task is certainly the mo...

Πίνακας περιεχομένων:

• Section 1: Evidence for inflammation-associated depression
• Evidence for inflammation-associated depression
• Role of inflammation in the development of neuropsychiatric symptom domains
• Inflammation-associated comorbidity
• Section 2: Mechanisms of inflammation-associated depression
• Mechanisms of inflammation-associated depression Immune-to-brain communication pathways and cytokines
• Immune-to-brain communication pathways
• Mechanisms of inflammation-associated depression
• Role of the kynurenine metabolism pathway
• Depression in autoimmune diseases
• Stress-induced microglia activation
• Inflammation effects on brain glutamate
• The role of dopamine
• Brain structures implicated in inflammation-associated depression
• Role of kynurenine metabolism pathway
• Suicidality. Section 3: Clinical implications of inflammation-associated depression
• The promise and limitations of anti-inflammatory agents
• Are non-steroidal anti-inflammatory drugs
• Does diet matter?- Role of neuroimunological factors.