Non-canonical Cyclic Nucleotides
The cyclic purine nucleotides 3’,5’-cAMP and 3’,5’-cGMP are well-established second messengers. cGMP has recently been covered in a volume of the Handbook of Experimental Pharmacology (volume 191). In addition to 3’,5’-cAMP and 3’,5’-cGMP, so-called non-canonical cyclic nucleotides exist. These comp...
| Συγγραφή απο Οργανισμό/Αρχή: | |
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| Άλλοι συγγραφείς: | |
| Μορφή: | Ηλεκτρονική πηγή Ηλ. βιβλίο |
| Γλώσσα: | English |
| Έκδοση: |
Cham :
Springer International Publishing : Imprint: Springer,
2017.
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| Σειρά: | Handbook of Experimental Pharmacology,
238 |
| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- Part I: 3’,5’-cCMP and 3’,5’-cUMP as second messengers: cCMP and cUMP across the tree of life: From cCMP and cUMP generators to cCMP- and cUMP-regulated cell functions
- cCMP and cUMP in apoptosis: Concepts and methods
- Mammalian nucleotidyl cyclases and their nucleotide binding sites
- The Pseudomonas aeruginosa exoenzyme Y: A promiscuous nucleotidyl cyclase edema factor and virulence determinant
- Cyclic nucleotide monophosphates in plants and plant signalling
- cAMP-dependent protein kinase and cGMP-dependent protein kinase as cyclic nucleotide effectors
- Regulation of HCN ion channels by non-canonical cyclic nucleotides
- Identification of cCMP and cUMP substrate proteins and cross-talk between cNMPs
- Inactivation of non-canonical cyclic nucleotides: Hydrolysis and transport
- Part II: 3’,5’-cIMP, 8-nitro-cGMP, 2’,3’-cNMPs and cyclic dinucleotides as signaling molecules: 3’,5’-cIMP as potential second messenger in the vascular wall
- The discovery of 2’,3’-cNMPs in mammalian systems: From rodents to humans
- 8-Nitro-cGMP: A novel protein-reactive cNMP and its emerging roles in autophagy
- Cyclic dinucleotides in the scope of the mammalian immune system
- Part III: Methods/Tools for cNMP research: Mass-spectrometric analysis of non-canonical cyclic nucleotides
- Medicinal chemistry of the noncanonical cyclic nucleotides cCMP and cUMP
- Holistic methods for the analysis of cNMP effects
- The chemistry of the non-canonical cyclic dinucleotide 2'3'-cGAMP and its analogs.
