Protein and Sugar Export and Assembly in Gram-positive Bacteria

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Bagnoli, Fabio (Επιμελητής έκδοσης), Rappuoli, Rino (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2017.
• Σειρά: Current Topics in Microbiology and Immunology, 404
• Θέματα: Medicine.; Medical microbiology.; Molecular biology.; Medical biochemistry.; Biomedicine.; Medical Microbiology.; Medical Biochemistry.; Molecular Medicine.

This book focuses on the envelope of Gram-positive bacteria including its composition, the latest discoveries in the mechanisms behind its assembly, and its role in pathogenesis. Furthermore, new applications in biotechnology and vaccine development involving these bacteria are discussed in detail....

Πίνακας περιεχομένων:

• Envelope structures of Gram-positive bacteria
• Translocation of proteins across the plasma membrane and cell envelope
• Type I signal peptidases
• The Sec system
• The twin-arginine protein translocation (Tat) system
• ExPortal: a microdomain for protein secretion in Gram-positive bacteria
• Spatial positioning of cell wall-anchored proteins
• Anchoring of LPXTG-like proteins to the cell wall envelope
• Export and processing of lipoproteins
• Pilus assembly in Gram-positive bacteria
• S-layers and related proteins: their structure, mechanisms of secretion and anchoring and their diverse functions
• Membrane translocation and assembly of sugar polymer precursors
• Type VII secretion systems
• Predicting subcellular localization of proteins by bioinformatics algorithms
• The secretome of Gram-positive bacteria
• Post-translocational folding of secretory proteins
• Protein secretion biotechnology in Gram-positive bacteria
• Exploiting Gram positive sortases for protein engineering.