TRAIL, Fas Ligand, TNF and TLR3 in Cancer

This volume provides the current understanding of death receptor's/TLR3 signaling regulation in cancer. Death receptors, including TRAIL-R1, TRAIL-R2, Fas and TNF-RI, owing to their ability to trigger apoptosis and to contribute to the elimination of cancer cells by the immune system have been...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Micheau, Olivier (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2017.
Σειρά:Resistance to Targeted Anti-Cancer Therapeutics, 12
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Resistance to TRAIL Pathway-Targeted Therapeutics in Cancer
  • TRAIL-R3/R4 and Inhibition of TRAIL Signalling in Cancer
  • IAPs and Resistance to Death Receptors in Cancer
  • Bcl-2 Proteins and TRAIL Resistance in Melanoma
  • Regulation of Caspase-Mediated Apoptosis by the Tumor Suppressor Par-4
  • Stem Cell Regulation by Death Ligands and Their Use in Cell Therapy
  • Atypical Immune Functions of CD95/CD95L
  • TLR3 is a Death Receptor Target in Cancer Therapy
  • Fas/CD95, Lipid Rafts and Cancer
  • Role of Sphingolipids in Death Receptor Signalling
  • Post-Translational Modifications and Death Receptor Signalling
  • System Modeling of Receptor-Induced Apoptosis.