Data Analytics for Protein Crystallization

• Main Authors: Pusey, Marc L. (Author), Aygün, Ramazan Savaş (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2017.
• Series: Computational Biology, 25
• Subjects: Computer science.; Molecular biology.; Biotechnology.; Data mining.; Image processing.; Bioinformatics.; Computer Science.; Computational Biology/Bioinformatics.; Data Mining and Knowledge Discovery.; Image Processing and Computer Vision.; Molecular Medicine.

This unique text/reference presents an overview of the computational aspects of protein crystallization, describing how to build robotic high-throughput and crystallization analysis systems. The coverage encompasses the complete data analysis cycle, including the set-up of screens by analyzing prior...

Table of Contents:

• Introduction to Protein Crystallization
• Scoring and Phases of Crystallization
• Computational Methods for Protein Crystallization Screening
• Robotic Image Acquisition
• Classification of Crystallization Trial Images
• Crystal Growth Analysis
• Focal Stacking for Crystallization Microscopy
• Crystal Image Region Segmentation
• Visualization
• Other Structure Determination Methods
• Future of Computational Protein Crystallization.