Tumor Organoids

• Corporate Author: SpringerLink (Online service)
• Other Authors: Soker, Shay (Editor, http://id.loc.gov/vocabulary/relators/edt), Skardal, Aleksander (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Humana, 2018.
• Edition: 1st ed. 2018.
• Series: Cancer Drug Discovery and Development,
• Subjects: Cancer research.; Cancer Research.

Cancer cell biology research in general, and anti-cancer drug development specifically, still relies on standard cell culture techniques that place the cells in an unnatural environment. As a consequence, growing tumor cells in plastic dishes places a selective pressure that substantially alters the...

Table of Contents:

• Techniques to Produce and Culture Lung Tumor Organoids
• Tissue Organoids: Liver
• Mammary Gland Organoids
• Biofabrication Technologies for Developing In Vitro Tumor Models
• Three Dimensional In Vitro Tumor Platforms for Cancer Discovery
• Tissue-engineered models for studies of bone metastasis
• Building Better Tumor Models: Organoid Systems to Investigate Angiogenesis
• Microfluidics in cell and tissue studies
• Stiffness-tuned matrices for tumor cell studies
• Mathematical modeling of tumor organoids: toward personalized medicine.