Extracellular Matrix in Tumor Biology

This volume provides an overview on the influence of Extracellular Matrix (ECM) on tumor progression. It covers topics such as signaling induced by structural ECM proteins including collagen and fibronectin, the control of ECM deposition and the turnover in tumors. Also discussed are the migration o...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Brekken, Rolf A. (Editor), Stupack, Dwayne (Editor)
Format: Electronic eBook
Language:English
Published: Cham : Springer International Publishing : Imprint: Springer, 2017.
Series:Biology of Extracellular Matrix,
Subjects:
Online Access:Full Text via HEAL-Link
Description
Summary:This volume provides an overview on the influence of Extracellular Matrix (ECM) on tumor progression. It covers topics such as signaling induced by structural ECM proteins including collagen and fibronectin, the control of ECM deposition and the turnover in tumors. Also discussed are the migration of cells through basement membranes and the function of proteoglycans including lumican and veriscan in tumor progression. Biomaterial-based in-vitro models as well as C. elegans models of the tumor microenvironment are used to show how these models can lead to a greater understanding of the disease mechanisms that promote cancer progression.  The book addresses researchers working on cancer biology or ECM, and oncologists alike.
Physical Description:IX, 115 p. 23 illus., 22 illus. in color. online resource.
ISBN:9783319609072
ISSN:0887-3224