Extracellular Matrix in Tumor Biology

• Corporate Author: SpringerLink (Online service)
• Other Authors: Brekken, Rolf A. (Editor), Stupack, Dwayne (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2017.
• Series: Biology of Extracellular Matrix,
• Subjects: Medicine.; Cancer research.; Immunology.; Molecular biology.; Oncology.; Proteins.; Cell biology.; Biomedicine.; Cancer Research.; Molecular Medicine.; Receptors.; Cell Biology.

This volume provides an overview on the influence of Extracellular Matrix (ECM) on tumor progression. It covers topics such as signaling induced by structural ECM proteins including collagen and fibronectin, the control of ECM deposition and the turnover in tumors. Also discussed are the migration o...

Table of Contents:

• 1. The extracellular matrix of tumors: a focus on fibronectin and fibulin-5
• 2. Internalization of collagen: an important matrix turnover pathway in cancer
• 3. Lumican, a Small Leucine-Rich Proteoglycan, and Its Biological Function in Tumor Progression
• 4. Versican: Role in Cancer Tumorigenesis
• 5. Engineering advanced models of the glioblastoma microenvironment using biomaterials
• 6. Breaching and opening basement membrane barriers: the anchor cell leads the way.