Vitiligo

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Picardo, Mauro (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Taïeb, Alain (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2019.
• Έκδοση: 2nd ed. 2019.
• Θέματα: Dermatology.; Internal medicine.; Plastic surgery.; Human genetics.; Cell biology.; Internal Medicine.; Plastic Surgery.; Human Genetics.; Cell Biology.

Since the first edition of this book was published, new knowledge has been gained on Vitiligo. This widely revised and updated second edition, written by worldwide experts in the field, fully reflects this progress. The apparently, simple and poorly symptomatic presentation of the disease has been a...

Πίνακας περιεχομένων:

• Preface
• I Defining the Disease
• 1.1 historical aspects
• 1.2 definitions and classification
• 1.3 Epidemiology
• 1.4 Histopathology including electron microscopy
• 1.5 Clinical aspects Including natural history according to subsets
• Short introduction
• 1.5.1 vitiligo including acrofacial, universalis
• 1.5.2 segmental vitiligo Including clinical aspects
• 1.5.3 Mixed vitiligo
• 1.5.4 rare variants including inflammatory
• 1.5.5 subtypes of mucocutaneous pigment cell involvement: mucosal, hair follicle (leukotrichia), nevus cells (halo nevus)
• 1.5.6 extracutaneous melanocytes
• 1.5.7 Environmental triggers: Koebner phenomenon and occupational vitiligo
• 1.5.8 associated disorders and comorbidities includingautoimmune/inflammatory disorders, immunodeficiences, rare monogenic diseases
• 1.5.9 age and vitiligo: childhood, pregnancy, late-onset
• 1.5.10 vitiligo and skin of colour
• 1.6 assessment and scoring including QoL
• 1.7 Editor's synthesis
• II Understanding the Disease
• 2.1 pathophysiology overview
• Unifying concepts V-SV
• 2.2 methods to study vitiligo
• 2.2.1 in vivo confocal microscopy and other noninvasive techniques
• 2.2.2 animal models
• 2.2.3 in vitro
• 2.3 critical assessment of published data on vitiligo Short introduction
• 2.3.1 Genetics
• 2.3.2 epigenetics
• 2.3.3 melanocyte stability
• 2.3.4 oxidative stress and intrinsic melanocyte defects
• 2.3.5 immunity (innate, adaptive). Innate and adaptive separated
• 2.3.6 peptides, growth factors including POMC and family
• 2.3.7 Stem cells
• 2.3.8 other defects and mechanisms
• 2.4 pathophysiology of segmental vitiligo
• 2.5 Editor's synthesis
• III Treating the Disease
• 3.1 management overview
• What has changed in a therapeutic perspective
• 3.2 discussion of available and new therapies
• 3.2.1 medical therapies
• 3.2.2 phototherapies
• 3.2.3 surgical therapies
• 3.2.4 depigmenting therapies
• 3.3combined/sequential/integrated therapies including maintenance therapy
• 3.4 camouflage
• 3.5 photoprotection
• 3.6 age, gender, ethnic skin, specific locations
• 3.7 psychological intervention
• 3.8 patient's perspectives
• 3.9 discussion of empirical, traditional, alternative approaches
• 3.10 evidence-based medicine perspective and guidelines
• 3.11 beyond guidelines
• 3.12 editor's synthesis and perspectives
• Subject Index. .