Precision Medicine, CRISPR, and Genome Engineering Moving from Association to Biology and Therapeutics /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Tsang, Stephen H. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2017.
• Σειρά: Advances in Experimental Medicine and Biology, 1016
• Θέματα: Life sciences.; Human genetics.; Ophthalmology.; Agriculture.; Stem cells.; Regenerative medicine.; Tissue engineering.; Life Sciences.; Regenerative Medicine/Tissue Engineering.; Stem Cells.; Human Genetics.

This book presents descriptive overviews of gene editing strategies across multiple species while also offering in-depth insight on complex cases of application in the field of tissue engineering and regenerative medicine.  Chapters feature contributions from leaders in stem cell therapy and biology...

Πίνακας περιεχομένων:

• Part 1. Introduction to the CRISPR Revolution.- 1. Viral Vectors, Engineered Cells and the CRISPR Revolution
• 2.  Combining Engineered Nucleases with Adeno-associated Viral Vectors for Therapeutic Gene Editing
• Part 2. CRISPR in Model Systems
•  3. From Reductionism to Holism: Toward a More Complete View of Development through Genome Engineering
• 4. Genome Engineering in Mice
• 5. Genome Editing to Study Ca2+ Homeostasis in Zebrafish Cone Photoreceptors
• 6. From Prokaryotic Immune Systems to Plant Genome Editing Tools
• 7. Part 3. The Future of CRISPR
• 7. Using High-throughput Gene Editing to Identify Therapeutic Targets in the Noncoding Genome
• 8. CRISPR in the Retina: Evaluation of Future Potential
• 9. The Future of CRISPR Applications in the Lab, the Clinic and Society.