Biomedical Applications of Acridines Derivatives, Syntheses, Properties and Biological Activities with a Focus on Neurodegenerative Diseases /

• Κύριοι συγγραφείς: Ježek, Jan (Συγγραφέας), Hlaváček, Jan (Συγγραφέας), Šebestík, Jaroslav (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2017.
• Σειρά: Progress in Drug Research, 72
• Θέματα: Chemistry.; Neurochemistry.; Pharmacology.; Bioorganic chemistry.; Medicinal chemistry.; Nucleic acids.; Proteins.; Medicinal Chemistry.; Pharmacology/Toxicology.; Protein-Ligand Interactions.; Bioorganic Chemistry.; Nucleic Acid Chemistry.

This book describes applications of acridines for the treatment of various neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and various prion diseases, and discusses the potential of acridines in neuro-regenerative medicine. Using modern data-mining software, it presents...

Πίνακας περιεχομένων:

• Preliminary ToC 1 Introduction
• 2 Nomenclature
• 3. Syntheses
• 4. Interactions of acridines with nucleic acids
• 5. Intercations with proteins
• 6. Applications for treament of neurodegenerative diseases
• 7. Some applications of selective toxicities of acridines
• 8. Acridine on dendrimeric carriers
• 9 Acridines used for staining
• 10 Miscellaneous
• 11 Conclusions and outlook.