A Network-Based Approach to Cell Metabolism From Structure to Flux Balances /
This thesis uses a systems-level approach to study the cellular metabolism, unveiling new mechanisms and responses that were impossible to reach with traditional reductionists procedures. The results reported here have a potential application in areas like metabolic engineering and disease treatment...
Κύριος συγγραφέας: | |
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Συγγραφή απο Οργανισμό/Αρχή: | |
Μορφή: | Ηλεκτρονική πηγή Ηλ. βιβλίο |
Γλώσσα: | English |
Έκδοση: |
Cham :
Springer International Publishing : Imprint: Springer,
2017.
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Σειρά: | Springer Theses, Recognizing Outstanding Ph.D. Research,
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Θέματα: | |
Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- Cellular Metabolism at the Systems Level
- Methods and Data
- Structural Knockout Cascades in Metabolic Networks
- Effects of Reaction Knockouts on Steady States of Metabolism
- Detection of Evolution and Adaptation Fingerprints in Metabolic Networks
- Assessing FBA Optimal States in the Feasible Flux Phenotypic Space
- Conclusions.