CFTR and Cystic Fibrosis From Structure to Function /

• Main Author: Farinha, Carlos M. (Author, http://id.loc.gov/vocabulary/relators/aut)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2018.
• Edition: 1st ed. 2018.
• Series: Protein Folding and Structure,
• Subjects: Medicinal chemistry.; Proteins .; Respiratory organs-Diseases.; Human genetics.; Molecular biology.; Medicinal Chemistry.; Protein Structure.; Pneumology/Respiratory System.; Human Genetics.; Molecular Medicine.

This Brief is devoted to the CFTR protein and cystic fibrosis, and it provides an updated perspective of the genetic, functional and cellular processes involved in this conformational disorder. Starting with a historical perspective on cystic fibrosis and its clinical features, the author departs in...