CFTR and Cystic Fibrosis From Structure to Function /

• Κύριος συγγραφέας: Farinha, Carlos M. (Συγγραφέας, http://id.loc.gov/vocabulary/relators/aut)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2018.
• Έκδοση: 1st ed. 2018.
• Σειρά: Protein Folding and Structure,
• Θέματα: Medicinal chemistry.; Proteins .; Respiratory organs-Diseases.; Human genetics.; Molecular biology.; Medicinal Chemistry.; Protein Structure.; Pneumology/Respiratory System.; Human Genetics.; Molecular Medicine.

This Brief is devoted to the CFTR protein and cystic fibrosis, and it provides an updated perspective of the genetic, functional and cellular processes involved in this conformational disorder. Starting with a historical perspective on cystic fibrosis and its clinical features, the author departs in...

Πίνακας περιεχομένων:

• Cystic fibrosis: an overview
• CFTR gene and protein
• CFTR in the cell
• CFTR function
• Therapies aimed at correcting the basic defect.