In Vivo Reprogramming in Regenerative Medicine

There have been significant improvements in the development of cell based therapies; however, current treatment strategies still suffer from some problems: the need for long in vitro culture conditions, inefficient delivery of cells by scaffolds and low incorporation and grafting efficiencies. There...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Yilmazer, Açelya (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cham : Springer International Publishing : Imprint: Humana Press, 2017.
Σειρά:Stem Cell Biology and Regenerative Medicine,
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
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024 7 |a 10.1007/978-3-319-65720-2  |2 doi 
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245 1 0 |a In Vivo Reprogramming in Regenerative Medicine  |h [electronic resource] /  |c edited by Açelya Yilmazer. 
264 1 |a Cham :  |b Springer International Publishing :  |b Imprint: Humana Press,  |c 2017. 
300 |a XVII, 103 p. 15 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
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490 1 |a Stem Cell Biology and Regenerative Medicine,  |x 2196-8985 
505 0 |a Chapter 1. Introduction to in vivo cell Reprogramming Technology -- Chapter 2. In vivo Reprogramming for Regenerating Insulin-Secreting Cells -- Chapter 3. Direct Reprogramming to Beta Cells -- Chapter 4. In vivo Lineage Reprogramming of Fibroblasts to Cardiomyocytes for Heart Regeneration -- Chapter 5: In vivo cell Reprogramming for Long-term Pluripotency -- Chapter 6: In vivo Transient Reprogramming Towards Pluripotency for Tissue Repair and Regeneration -- Chapter 7. Challenges and Future Perspectives for in vivo Reprogramming Technology. 
520 |a There have been significant improvements in the development of cell based therapies; however, current treatment strategies still suffer from some problems: the need for long in vitro culture conditions, inefficient delivery of cells by scaffolds and low incorporation and grafting efficiencies. Therefore, in vivo reprogramming has emerged as a novel treatment technology. In the process of in vivo reprogramming, cells switch to another cell type within the living organism. Leaders in the field discuss how in vivo reprogramming can be used for tissue repair and regeneration in different organs, including pancreas, liver and heart. Furthermore, recent studies on in vivo cell reprogramming towards pluripotency are also reviewed. Current challenges of these preclinical studies are discussed and hypothesis and suggestions are given in order to improve the current strategies to achieve translation into clinic. . 
650 0 |a Life sciences. 
650 0 |a Surgical transplantation. 
650 0 |a Stem cells. 
650 0 |a Cell culture. 
650 0 |a Regenerative medicine. 
650 0 |a Tissue engineering. 
650 1 4 |a Life Sciences. 
650 2 4 |a Regenerative Medicine/Tissue Engineering. 
650 2 4 |a Stem Cells. 
650 2 4 |a Cell Culture. 
650 2 4 |a Transplant Surgery. 
700 1 |a Yilmazer, Açelya.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
776 0 8 |i Printed edition:  |z 9783319657196 
830 0 |a Stem Cell Biology and Regenerative Medicine,  |x 2196-8985 
856 4 0 |u http://dx.doi.org/10.1007/978-3-319-65720-2  |z Full Text via HEAL-Link 
912 |a ZDB-2-SBL 
950 |a Biomedical and Life Sciences (Springer-11642)