Collagenase in Dupuytren Disease

• Corporate Author: SpringerLink (Online service)
• Other Authors: Pajardi, Giorgio (Editor, http://id.loc.gov/vocabulary/relators/edt), Badalamente, Marie A. (Editor, http://id.loc.gov/vocabulary/relators/edt), Hurst, Lawrence C. (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2018.
• Edition: 1st ed. 2018.
• Subjects: Orthopedics.; Plastic surgery.; Rehabilitation.; Conservative Orthopedics.; Surgical Orthopedics.; Plastic Surgery.

This book offers detailed guidance on the use of collagenase, or enzymatic fasciotomy, as a nonsurgical treatment for Dupuytren's contracture and explains its role in relation to the other forms of treatment, including open fasciectomy, needle aponeurotomy, and lipofilling. Clear guidance is pr...

Table of Contents:

• 1 Biochemistry and mechanism of action of collagen
• 2 Pre-Clinical evaluation and early clinical trials in USA
• 3 Dupuytren's Disease: topographic anatomy of lesions
• 4 Experimental phase in Europe: protocol and first results
• 5 Preparation, injection and traction procedures (Pearls and Tips & Tricks): technical evolution
• 6 First web space, thumb, and nodules
• 7 Rehabilitation after treatment
• 8 Collagenase today: follow-up studies, recurrence, dosage, drug safety
• 9 American and European Regulations
• 10 Collagenase: future perspectives. .