Resistance to Targeted Therapies in Breast Cancer

• Corporate Author: SpringerLink (Online service)
• Other Authors: Prosperi, Jenifer R. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2017.
• Series: Resistance to Targeted Anti-Cancer Therapeutics, 16
• Subjects: Medicine.; Cancer research.; Biomedicine.; Cancer Research.

We present an in-depth description of resistance to targeted therapies in breast cancer. Targeted therapies discussed here include those used to treat ER+ or Her2+ breast cancers (i.e., Tamoxifen or trastuzumab) or those targeting signaling pathways aberrantly activated in triple negative breast can...

Table of Contents:

• Invasive Breast Cancer Therapy 2017: How Well Are We Hitting The Target?
• Resistance to HER2-targeted therapy
• Endocrine Resistance and Breast Cancer Stem Cells – The Inflammatory Connection That Could Lead to New and Improved Therapy Outcomes
• EGFR Resistance
• Targeting FGFR for the treatment of breast cancer
• Targeted Therapies in Breast Cancer
• Future paradigm of breast cancer resistance and treatment.