Mitochondrial Biology and Experimental Therapeutics

This book addresses the therapeutic strategies to target mitochondrial metabolism in diseases where the function of that organelle is compromised, and it discusses the effective strategies used to create mitochondrial-targeted agents that can become commercially available drug delivery platforms. Th...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Oliveira, Paulo J. (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2018.
Έκδοση:1st ed. 2018.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Target Mitochondria
  • SECTION I-Mitochondrial Biology
  • Introduction: Mitochondria: the cell furnace
  • MItochondria: Where are They Coming From?
  • Mitochondrial Dynamics: A journey from Mitochondrial Morphology to MItochondrial Function and Quality
  • Mitochondrial ROS, Oxidative Stress.and Aging- The Mitochondrial Permeability Transition Pore
  • Mitochondrial Regulation of Cell Death
  • MItochondria in Liver Diseases
  • Mitochondria in Liver Regeneration,Energy Metabolism, and Posthepatectomy Liver Dysfunction
  • MItochondrial Remodeling in Cancer
  • Mitochondria in Kidney Disease
  • CNS diseases and disruption of Mitochondria
  • Mitochondrial disruption in cardiovascular diseases
  • .Drug-inducing Mitochondrial Toxicity
  • MItochondrial DNA: Functions and Role in Acquired Diseases
  • SECTION II-MItochondrial Therapeutics: From the Bench to Industry and Patient
  • The Evolution of Mitochondrial Toxicity Assessment in Industry
  • Designing Mitochondrial-Active Molecules: The Road to MitoQ and Beyond
  • Recovering Mitochondrial Function in Patients' Fibroblasts
  • Targeting Mitochondria with Sweat: Improving Mitochondrial Function with Physical Activity
  • Modulation of Cell Fate by Tauroursodexycholic Acid: All Paths Lead to Mitochondria
  • Pharmacological Targeting of the Mitchondrial Permeability Transition Pore
  • Strategies to Preserve/Improve Mitochondrial Function in Organ Preservation Solutions
  • MItochondrial Targeted Redox Active Compounds and the Astrocytemotoneuron Axis: relevance for the Treatment of Amyotrophic Lateral Sclerosis
  • Targeting the Mitochondrial Genome Through a Nanocarrier and the Regulation of the Mitochondrial Gene Experssion
  • Mitochoncrial Dysfunction and Chronic Disease: Treatment with Membrane Lipid Replacement and other Natural Supplements
  • Development of Mitochondrial-Directed Plastoquinones
  • Targeted Mitochondrial Genome Editing
  • Targeting Therpeutic Nucleic Acids into Mitochondria: A Long Challenge
  • Cell Permeable Peptides Targeting Mitochondria
  • MItochondrial -Directed Cancer Therapy
  • SkQ1: The Road from the Bench to the Market
  • MItochondrial Follies: Comic.