Fluorescent Tools for Imaging Oxidative Stress in Biology

• Main Author: Kaur, Amandeep (Author, http://id.loc.gov/vocabulary/relators/aut)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2018.
• Edition: 1st ed. 2018.
• Series: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Subjects: Analytical chemistry.; Oxidative stress.; Biophysics.; Biological physics.; Biomedical engineering.; Physical chemistry.; Analytical Chemistry.; Oxidative Stress.; Biological and Medical Physics, Biophysics.; Biomedical Engineering/Biotechnology.; Physical Chemistry.

This thesis advances the long-standing challenge of measuring oxidative stress and deciphering its underlying mechanisms, and also outlines the advantages and limitations of existing design strategies. It presents a range of approaches for the chemical synthesis of fluorescent probes that detect rev...

Table of Contents:

• Introduction
• Flavin based redox probes
• FRET based ratiometric redox probes
• Mitochondrially-targeted ratiometric redox probes
• Nicotinamide based ratiometric probes
• In cellulo studies
• Ex vivo studies
• Non-mammalian systems
• Conclusions
• Experimental Methods. .