New Organocatalytic Strategies for the Selective Synthesis of Centrally and Axially Chiral Molecules

• Main Author: Di Iorio, Nicola (Author, http://id.loc.gov/vocabulary/relators/aut)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2018.
• Edition: 1st ed. 2018.
• Series: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Subjects: Catalysis.; Organic chemistry.; Medicinal chemistry.; Organic Chemistry.; Medicinal Chemistry.

This thesis discusses the use of asymmetric organic catalysis for the direct enantioselective synthesis of complex chiral molecules, and by addressing the many aspects of both vinylogy and atropisomerism, it appeals to researchers and scholars interested in both areas. Organocatalysis is a relativel...

Table of Contents:

• Introduction
• The Vinylogous Reactivity of Oxindoles Bearing Non-symmetric 3-Alkylidene Groups
• Targeting the Remote Control of Axial Chirality in N-(2-tert-Butylphenyl)Succinimides via a Desymmetrization Strategy
• Direct Catalytic Synthesis of C(sp2)-C(sp3) Atropisomers with Simultaneous Control of Central and Axial Chirality.