Type IV Secretion in Gram-Negative and Gram-Positive Bacteria

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Backert, Steffen (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Grohmann, Elisabeth (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2017.
• Έκδοση: 1st ed. 2017.
• Σειρά: Current Topics in Microbiology and Immunology, 413
• Θέματα: Medical microbiology.; Immunology.; Infectious diseases.; Gastroenterology .; Medical Microbiology.; Infectious Diseases.; Gastroenterology.

Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a large variety of target cells. This volume summarizes our current knowledge of the large variety and structural diversi...

Πίνακας περιεχομένων:

• Biological diversity of prokaryotic type IV secretion systems.- Evolution of type IV secretion systems and their substrates.- Structural and molecular biology of type IV secretion systems.- Relaxosome formation and transfer of broad-host range plasmids Gram-negative bacteria.- Mechanisms of conjugative transfer by Gram-positive broad-host range plasmids.- Social behavior and decision making in bacterial conjugation
• Structure and chemical biology approaches to understand type IV secretion system function and inhibition
• Type IV secretion systems: A pivotal tool to establish intracellular lifestyle by pathogens.- Subversion of host target cells by the Legionella type IV secretion system.- Role of multiple type IV secretion systems in Bartonella infections.- Requirements for T4SS effector protein translocation and function by the Coxiella Dot/Icm system.- Composition and function of the Helicobacter pylori cag type IV secretion system.- Secretion of chromosomal DNA by the gonococcal type IV secretion system. .