The Heterogeneity of Cancer Metabolism

• Corporate Author: SpringerLink (Online service)
• Other Authors: Le, Anne (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2018.
• Edition: 1st ed. 2018.
• Series: Advances in Experimental Medicine and Biology, 1063
• Subjects: Cancer research.; Immunology.; Cancer Research.

Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabo...

Table of Contents:

• Part 1: The metabolism of cancer cells
• Chapter 1: Glucose Metabolism
• Chapter 2: Glutamine Metabolism
• Chapter 3: Amino Acid Metabolism
• Chapter 4: Lipid Metabolism
• Chapter 5: Epigenetics and oncometabolites
• Part 2: Heterogeneity of Cancer Metabolism - Chapter 1: Specific oncogenetic mutations lead to specific metabolic phenotypes within the same tissue of origin
• Chapter 2: Intratumoral heterogeneity of cancer cell metabolism
• - Chapter 3: Differential metabolism in vitro and in vivo
• Part 3: Carcinoma associated fibroblasts
• Chapter 1: Characteristics of CAF's
• Chapter 2: Reverse Warbug EFF
• Chapter 3: Metabolic exchange between CAFs and cancer cells. .