Coordinating Organismal Physiology Through the Unfolded Protein Response

This volume reviews the current research focused on the functional importance of unfolded protein response (UPR) signaling in the context of health and disease. The chapters present cutting-edge work describing the diverse functions of UPR signaling critical for regulating cellular and organismal ph...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Wiseman, R. Luke (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Haynes, Cole M. (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2018.
Έκδοση:1st ed. 2018.
Σειρά:Current Topics in Microbiology and Immunology, 414
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
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505 0 |a Adapting Secretory Proteostasis and Function Through the Unfolded Protein Response -- Cell Non-Autonomous UPRER Signaling -- The unfolded protein response in the immune cell development: Putting the caretaker in the driving seat -- Mitochondria associated membranes and ER stress -- Coordinating Organismal Metabolism during Protein Misfolding in the ER Through the Unfolded Protein Response -- ER stress and neurodegenerative disease: a cause or effect relationship?- Driving cancer tumorigenesis and metastasis through UPR signaling -- ER Protein Quality Control and the Unfolded Protein Response in the Heart. 
520 |a This volume reviews the current research focused on the functional importance of unfolded protein response (UPR) signaling in the context of health and disease. The chapters present cutting-edge work describing the diverse functions of UPR signaling critical for regulating cellular and organismal physiology under physiologic and pathologic conditions. Written by internationally respected scientists, this volume is designed to provide a broad view of the diverse functional importance of UPR, and as such appeals to clinicians and academic researchers alike. 
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