Coordinating Organismal Physiology Through the Unfolded Protein Response

• Corporate Author: SpringerLink (Online service)
• Other Authors: Wiseman, R. Luke (Editor, http://id.loc.gov/vocabulary/relators/edt), Haynes, Cole M. (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2018.
• Edition: 1st ed. 2018.
• Series: Current Topics in Microbiology and Immunology, 414
• Subjects: Immunology.; Human physiology.; Neurosciences.; Cancer research.; Infectious diseases.; Human Physiology.; Cancer Research.; Infectious Diseases.

This volume reviews the current research focused on the functional importance of unfolded protein response (UPR) signaling in the context of health and disease. The chapters present cutting-edge work describing the diverse functions of UPR signaling critical for regulating cellular and organismal ph...

Table of Contents:

• Adapting Secretory Proteostasis and Function Through the Unfolded Protein Response
• Cell Non-Autonomous UPRER Signaling
• The unfolded protein response in the immune cell development: Putting the caretaker in the driving seat
• Mitochondria associated membranes and ER stress
• Coordinating Organismal Metabolism during Protein Misfolding in the ER Through the Unfolded Protein Response
• ER stress and neurodegenerative disease: a cause or effect relationship?- Driving cancer tumorigenesis and metastasis through UPR signaling
• ER Protein Quality Control and the Unfolded Protein Response in the Heart.