Voltage-gated Sodium Channels: Structure, Function and Channelopathies

• Corporate Author: SpringerLink (Online service)
• Other Authors: Chahine, Mohamed (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2018.
• Edition: 1st ed. 2018.
• Series: Handbook of Experimental Pharmacology, 246
• Subjects: Pharmacology.; Human genetics.; Human physiology.; Proteins .; Pharmacology/Toxicology.; Human Genetics.; Human Physiology.; Protein Structure.
• Physical Description: X, 450 p. 80 illus., 55 illus. in color. online resource.
• ISBN: 9783319902845
• ISSN: 0171-2004 ;
• DOI: 10.1007/978-3-319-90284-5

This book provides a timely state-of-the-art overview of voltage-gated sodium channels, their structure-function, their pharmacology and related diseases. Among the topics discussed are the structural basis of Na+ channel function, methodological advances in the study of Na+ channels, their pathophysiology and drugs and toxins interactions with these channels and their associated channelopathies.