Stress, Trauma and Synaptic Plasticity

• Main Authors: Bennett, Maxwell (Author, http://id.loc.gov/vocabulary/relators/aut), Lagopoulos, Jim (http://id.loc.gov/vocabulary/relators/aut)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2018.
• Edition: 1st ed. 2018.
• Subjects: Neurosciences.; Neurobiology.; Neurology .; Neurology.

This book provides detailed insights into the cellular and molecular alterations that occur in the brain following stress and trauma. The changes to the grey matter in certain areas of the brain are similar in stressed humans and animals, with the most likely basis for these changes being the degene...

Table of Contents:

• Grey matter changes in the brain following stress and trauma
• Synaptic changes responsible for grey matter changes in the brain of animal models following stress
• Identification of the core neural network subserving PTSD in animal models and their modulation
• Modulation of the core neural network in stress: the role of Brain Derived Neurotrophic Factor & LTP
• Modulation of the core neural network in stress: the role of Endocannabinoids & LTD
• Functioning of the core neural network in fear and extinction
• Modulation of the core synaptic network in extinction: the role of Brain Derived Neurotrophic Factor
• Appendix 1: F-actin determination of dendritic spine integrity
• Appendix 2: Regulation of NMDA receptors. .