Diabetic Nephropathy Pathophysiology and Clinical Aspects /

This book provides an overview of the most up-to-date research on diabetic nephropathy and the current understanding of its pathogenesis, clinical features and socio-economic developments. Written by leading experts in the field, it provides a comprehensive synthesis of clinical and pathophysiologic...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Roelofs, Joris J. (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Vogt, Liffert (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2019.
Έκδοση:1st ed. 2019.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • 1. Diabetic nephropathy - Scope of the problem
  • Historical overview of diabetic kidney disease
  • Clinical features and natural course of diabetic nephropathy
  • Global, regional and ethnic differences in diabetic nephropathy
  • Diabetic nephropathy in children and adolescents
  • Renal disease in obesity, metabolic syndrome and diabesity
  • 2. Pathophysiology and clinical pathology of the diabetic kidney
  • Introduction to pathogenetic mechanisms of diabetic nephropathy
  • The genetics of diabetic nephropathy
  • Pathology of the kidney in diabetes
  • 3. The glomerulus
  • The mesangial cell in diabetic nephropathy
  • The glomerular endothelium in diabetic nephropathy - role of heparanase
  • The podocyte in diabetic nephropathy: recent advances
  • Inflammatory processes in diabetic glomeruli
  • 4. The tubulointerstitium
  • Proteinuria and tubulotoxicity
  • Tubulo-glomerular communication in diabetic nephropathy
  • Mechanisms of interstitial fibrosis in diabetic nephropathy
  • 5. Microvascular involvement
  • Microvascular damage and hemodynamic alterations in diabetic nephropathy
  • Coagulation and hemostasis in diabetic nephropathy
  • Renal hemodynamics in diabetic kidney disease - relevance for intervention
  • Microvascular complications in the eye: diabetic retinopathy
  • 6. Macrovascular involvement
  • Hypertension in diabetic kidney disease
  • Macrovascular involvement in diabetes - renal artery stenosis
  • Atherosclerosis and diabetic nephropathy
  • 7. Experimental designs
  • Animal models of diabetic kidney disease
  • Clinical trial and error in diabetic nephropathy
  • 8. Therapy of diabetic nephropathy
  • Treatment goals in diabetic nephropathy
  • Kidney transplantation and diabetic nephropathy
  • 9. Future developments
  • Health programs in low- and middle-income countries
  • OMICs in diabetic kidney disease
  • Future and novel compounds in the treatment of diabetic nephropathy.