Delta Opioid Receptor Pharmacology and Therapeutic Applications

• Corporate Author: SpringerLink (Online service)
• Other Authors: Jutkiewicz, Emily M. (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2018.
• Edition: 1st ed. 2018.
• Series: Handbook of Experimental Pharmacology, 247
• Subjects: Pharmacology.; Neurosciences.; Human physiology.; Pharmacology/Toxicology.; Human Physiology.

This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds an...

Table of Contents:

• Part 1. DOPR Ligands
• 1. Delta Opioid Receptor (DOR) Ligands and Pharmacology: Development of Indolo- and Quinolinomorphinan Derivatives Based on the Message-Address Concept
• 2. Multifunctional Opioid Ligands
• 3. Contribution of Delta-Opioid Receptors to Pathophysiological Events Explored by Endogenous Enkephalins
• Part 2. DOPR Signaling
• 4. Ligand-Directed Signaling at the Delta Opioid Receptor
• 5. Delta Opioid Receptor Expression and Function in Primary Afferent Somatosensory Neurons
• 6. Evidence and Function Relevance of Native DOR-MOR Heteromers
• Part 3. DOPR and Disease
• 8. The Delta Opioid Receptor in Pain Control
• 9. Delta Opioid Receptors and Modulation of Mood and Emotion
• 10. Delta Opioid Pharmacology in Relation to Alcohol Behaviors
• 11. Delta Opioid Receptors: Learning and Motivation
• 12. Delta Opioid Pharmacology in Parkinson's Disease
• 13. Delta Opioid Receptor and Peptide: A Dynamic Therapy for Stroke and Other Neurological Disorders
• 14. Delta Opioid Receptors and Cardioprotection
• 15. The Roles of Opioid Receptors in Cutaneous Wound Healing. .