Predictive Biomarkers in Oncology Applications in Precision Medicine /
This book provides a collection of ingeniously organized, well-illustrated, and up-to-date authoritative chapters divided into five sections that are clear and easy to understand. Early sections provide a concise and richly illustrated overview of biomarkers by introducing basic terminologies and an...
| Συγγραφή απο Οργανισμό/Αρχή: | |
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| Άλλοι συγγραφείς: | , |
| Μορφή: | Ηλεκτρονική πηγή Ηλ. βιβλίο |
| Γλώσσα: | English |
| Έκδοση: |
Cham :
Springer International Publishing : Imprint: Springer,
2019.
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| Έκδοση: | 1st ed. 2019. |
| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- Introduction to Predictive Biomarkers: definitions and characteristics
- Introduction to clinical trials, clinical trial designs and statistical terminology used for predictive biomarker research and validation
- Overview of Methods Used in Predictive Biomarker Studies in a Molecular Anatomic Pathology Laboratory
- Significance of Immunohistochemistry and In Situ Hybridization Techniques for Predictive Biomarker Studies
- Overview of PCR-based Technologies and Multiplexed Gene Analysis for Biomarker Studies
- Introduction to Microarray Technology
- Digital and Computational Pathology for Biomarker Discovery
- Detection of Predictive Biomarkers Using Liquid Biopsies
- Measurement of Predictive Cancer Biomarkers by Flow Cytometry
- Personalized Cancer Treatment and Patient Stratification Using Massive Parallel Sequencing (MPS) and Other OMICs Data
- Bioinformatic Methods and Resources for Biomarker Discovery, Validation, Development, and Integration
- Overview of Cell Signaling Pathways in Cancer
- Steroid Hormone and Nuclear Receptor signaling pathways
- Protein kinase C Signaling in Carcinogenesis
- Roles of Rho/ROCK in Cancer Signaling
- Mitogen Activated Protein Kinase (MAPK) Signaling
- Notch Signaling Pathway in Carcinogenesis
- Signaling of the ErbB receptor Family in Carcinogenesis and the Development of Targeted Therapies
- Signaling Pathways in Tumor Angiogenesis and Anti-angiogenic Therapies in Human Cancer
- Role of PI3K/AKT/mTOR in Cancer Signaling
- Met Signaling in Carcinogenesis
- Role of Insulin-like Growth Factor Receptors in Cancer Signaling
- Role of Wnt/β-catenin Pathway in Cancer Signaling
- Hedgehog Signaling in Carcinogenesis
- TGF-β and the SMAD Signaling Pathway in Carcinogenesis
- Role of JAK-STAT Pathway in Cancer Signaling
- NF-kB signaling pathways in Carcinogenesis
- Immune-Signaling in Carcinogenesis
- Predictive Biomarkers and Targeted Therapies in Immuno-Oncology
- Role of Protein Tyrosine Phosphatases in Cancer Signaling
- Predictive and Prognostic Biomarkers in Myeloid Neoplasms
- Predictive Biomarkers and Targeted Therapies for Lymphoid Malignancies
- Targeted Therapies for Pediatric Central Nervous System Tumors
- Predictive Biomarkers and Targeted Therapies in Adult Brain Cancers
- Predictive Biomarkers and Targeted Therapies in Breast Cancer
- Predictive Biomarkers in Lung Cancer
- Predictive Biomarkers and Targeted Therapies in Genitourinary Cancers
- Predictive Biomarkers and Targeted Therapies in Colorectal Cancer
- Predictive Markers and Targeted Therapies in Gastroesophageal Cancer (GEC)
- Predictive Biomarkers and Targeted Therapies in Hepatic, Pancreatic, and Biliary Cancers
- Gynecological Cancers & Head and Neck Cancers
- Predictive Biomarkers and Targeted Therapies in Head and Neck Cancer
- Predictive Biomarkers and Targeted Therapies in the Skin
- Predictive Biomarkers and Targeted Therapies in Sarcomas
- Predictive Markers and Targeted Therapies in Thyroid Cancer and Selected Endocrine Tumors
- The Response Evaluation Criteria in Solid Tumors (RECIST)
- IVDs and FDA Marketing Authorizations: A General Overview of FDA Approval Process of an IVD Companion Diagnostic Device in Oncology
- Quality Control of Immunohistochemical and In Situ hybridization Predictive Biomarkers for Patient Treatment: Experience from International Guidelines and International Quality Control Schemes
- Use of Companion Diagnostics (CDx) and Predictive Biomarkers for Cancer Targeted Therapy. Clinical Applications in Precision Medicine
- Policy issues in the clinical development and use of predictive biomarkers for molecular targeted therapies
- Role of central laboratories in research, validation and application of predictive biomarkers
- Prominent Precision Medicine Clinical Trials in Oncology Around the World
- Precision Medicine Clinical Trials: Successes and Disappointments, Challenges and Opportunities. Lessons Learnt
- FDA Approved Targeted Therapies in Oncology.
