Endocytosis and Signaling

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Lamaze, Christophe (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Prior, Ian (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2018.
• Έκδοση: 1st ed. 2018.
• Σειρά: Progress in Molecular and Subcellular Biology, 57
• Θέματα: Cell membranes .; Cell physiology.; Cell cycle.; Proteins .; Membrane Biology.; Cell Physiology.; Cell Cycle Analysis.; Protein Science.

This book focuses on the context dependency of cell signaling by showing how the endosomal system helps to structure and regulate signaling pathways. The location and concentration of signaling nodes regulate their activation cycles and engagement with distinct effector pathways. Whilst many cell si...

Πίνακας περιεχομένων:

• Preface
• The endosomal network: mediators and regulators of endosome maturation
• Integration of the endocytic system into the network of cellular functions
• GTPases Rac1 and Ras signaling from endosomes
• ESCRT and membrane protein ubiquitination
• Retromer and it's role in regulating signaling at endosomes
• The lysosome and intracellular signaling
• Interplay of endocytosis and growth factor receptor signaling
• Role of the endocytosis of caveolae in intracellular signaling and metabolism
• EGFR trafficking in physiology and cancer
• Evolving view of membrane trafficking and signaling systems for G protein-coupled receptors
• Endosomal trafficking during mitosis and Notch-dependent asymmetric division.