Molecular Analysis of B Lymphocyte Development and Activation

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Singh, Harinder (Επιμελητής έκδοσης), Grosschedl, Rudolf (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg, 2005.
• Σειρά: Current Topics in Microbiology and Immunology, 290
• Θέματα: Medicine.; Immunology.; Biomedicine.

The B lymphocyte lineage represents an important paradigm for exploring the molecular mechanisms underlying cell fate specification, differentiation and cellular activation. In the past five years, major advances have been achieved in our understanding of the transcriptional control of early B cell...

Πίνακας περιεχομένων:

• Gene Regulatory Networks Orchestrating B Cell Fate Specification, Commitment, and Differentiation
• Helix-Loop-Helix Proteins in Lymphocyte Lineage Determination
• Ikaros-Family Proteins: In Search of Molecular Functions During Lymphocyte Development
• Biochemistry of V(D)J Recombination
• The pre-B cell Receptor in B Cell Development: Recent Advances, Persistent Questions and Conserved Mechanisms
• Transcriptional Control of B Cell Activation
• Expression of MHC II Genes
• Class Switch Recombination: An Emerging Mechanism
• Blimp-1; Immunoglobulin Secretion and the Switch to Plasma Cells
• Wnt Signaling in Lymphopoiesis.