Genotype — Proteotype — Phenotype Relationships in Neurodegenerative Diseases

• Corporate Author: SpringerLink (Online service)
• Other Authors: Cummings, Jeffrey L. (Editor), Poncet, Michel (Editor), Hardy, John (Editor), Christen, Yves (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2005.
• Series: Research and Perspectives in Alzheimer's Disease,
• Subjects: Medicine.; Neurosciences.; Neurology.; Biomedicine.

Protein misfolding and other abnormalities of protein metabolism are increasingly recognized as central mechanisms in the pathophysiology of neurodegenerative disorders. Amyloid beta protein disturbances in Alzheimer’s disease, tau and ubiquitin protein abnormalities in frontotemporal dementias, pro...