Microarray Technology and Its Applications

• Corporate Author: SpringerLink (Online service)
• Other Authors: Müller, Uwe R. (Editor), Nicolau, Dan V. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2005.
• Series: Biological and Medical Physics, Biomedical Engineering,
• Subjects: Medicine.; Physical chemistry.; Biophysics.; Biological physics.; Biomedical engineering.; Nanotechnology.; Biomedicine.; Biomedicine general.; Biophysics and Biological Physics.; Biomedical Engineering.; Physical Chemistry.; Medicine/Public Health, general.

The genomics revolution would not have been possible without the 'parallelisation' offered by microarray technology. This technological - and commercial - success has been since emulated by other applications areas, with a tremendous amplification of innovation. This book describes the fun...

Table of Contents:

• General Microarray Technologies
• Array Formats
• Biomolecules and Cells on Surfaces — Fundamental Concepts
• Surfaces and Substrates
• Reagent Jetting Based Deposition Technologies for Array Construction
• Manufacturing of 2-D Arrays by Pin-printing Technologies
• Nanoarrays
• The Use of Microfluidic Techniques in Microarray Applications
• Labels and Detection Methods
• Marker-free Detection on Microarrays
• DNA Microarrays
• Analysis of DNA Sequence Variation in the Microarray Format
• High Sensitivity Expression Profiling
• Applications of Matrix-CGH (Array-CGH) for Genomic Research and Clinical Diagnostics
• Analysis of Gene Regulatory Circuits
• Protein Microarrays
• Protein, Antibody and Small Molecule Microarrays
• Photoaptamer Arrays for Proteomics Applications
• Biological Membrane Microarrays
• Cell & Tissue Microarrays
• Use of Reporter Systems for Reverse Transfection Cell Arrays
• Whole Cell Microarrays
• Tissue Microarrays for Miniaturized High-Throughput Molecular Profiling of Tumors
• Application of Microarray Technologies for Translational Genomics.