Protein Folding Kinetics Biophysical Methods /

• Main Author: Nölting, Bengt (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2006.
• Edition: Second Edition.
• Subjects: Life sciences.; Biotechnology.; Food > Biotechnology.; Biochemistry.; Proteins.; Biophysics.; Biological physics.; Life Sciences.; Protein Science.; Biochemistry, general.; Biophysics and Biological Physics.; Food Science.

The book gives a deep insight into the principles and concepts of the kinetic and structural resolution of fast chemical and biophysical reactions of proteins with emphasis on protein-folding reactions. The study of fast protein-folding reactions and the understanding of the folding paradox have sig...

Table of Contents:

• Structures of proteins
• Physical interactions that determine the properties of proteins
• Calculation of the kinetic rate constants
• High kinetic resolution of protein folding events
• Kinetic methods for slow reactions
• Resolution of protein structures in solution
• High structural resolution of transient protein conformations
• Experimental problems of the kinetic and structural resolution of reactions that involve proteins
• The folding pathway of a protein (barstar) at the resolution of individual residues from microseconds to seconds
• Highly resolved folding pathways and mechanisms of six proteins
• Structural determinants of the rate of protein folding
• Evolutionary computer programming of protein structure and folding
• Conclusions.