Developmental Biology of Neoplastic Growth

• Corporate Author: SpringerLink (Online service)
• Other Authors: Macieira-Coelho, Alvaro (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2005.
• Series: Progress in Molecular and Subcellular Biology, 40
• Subjects: Life sciences.; Cancer research.; Molecular biology.; Medical biochemistry.; Cell biology.; Developmental biology.; Life Sciences.; Developmental Biology.; Cancer Research.; Cell Biology.; Molecular Medicine.; Medical Biochemistry.

In this book, tumour growth is perceived as a deviation from the normal development of the human organism. The molecular, cellular, and tissue determinants of different tumours are discussed showing that each is a different disease, often corresponding to a particular developmental stage. The natura...

Table of Contents:

• The Hedgehog Signaling Pathway in Cancer
• Rho GTPases and Cancer
• Developmental Biology of Fibroblasts and Neoplastic Disease
• The Extracellular Matrix During Normal Development and Neoplastic Growth
• Wilms’ Tumor: Starting Off the Kidney All Over Again?
• Testicular Teratomas: Back to Pluripotent Stem Cells
• Tumor Suppressors APC and VHL: Gatekeepers of the Intestine and Kidney
• Hormonal and Stromal Regulation of Normal and Neoplastic Prostatic Growth
• Neoplastic Growth Through the Developmental Stages of the Organism.