Dislocation and Degradation of Proteins from the Endoplasmic Reticulum

• Corporate Author: SpringerLink (Online service)
• Other Authors: Wiertz, Emmanuel (Editor), Kikkert, Marjolein (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2005.
• Series: Current Topics in Microbiology and Immunology, 300
• Subjects: Medicine.; Medical microbiology.; Biomedicine.; Medical Microbiology.

The present volume of Current Topics in Microbiology and Immunology c- tains seven chapters that illuminate various aspects of a protein’s genesis and terminal fate in the endoplasmic reticulum (ER). This area is of immediate medical relevance and has blossomed, to no small extent, because of the st...

Table of Contents:

• The Secretory Capacity of a Cell Depends on the Efficiency of Endoplasmic Reticulum-Associated Degradation
• Recognition and Delivery of ERAD Substrates to the Proteasome and Alternative Paths for Cell Survival
• CPY* and the Power of Yeast Genetics in the Elucidation of Quality Control and Associated Protein Degradation of the Endoplasmic Reticulum
• The Role of the Ubiquitination Machinery in Dislocation and Degradation of Endoplasmic Reticulum Proteins
• The Role of p97/Cdc48p in Endoplasmic Reticulum-Associated Degradation: From the Immune System to Yeast
• The Ins and Outs of Intracellular Peptides and Antigen Presentation by MHC Class I Molecules
• Entry of Protein Toxins into Mammalian Cells by Crossing the Endoplasmic Reticulum Membrane: Co-opting Basic Mechanisms of Endoplasmic Reticulum-Associated Degradation.