Axonal Branching and Recovery of Coordinated Muscle Activity after Transection of the Facial Nerve in Adult Rats

• Κύριοι συγγραφείς: Angelov, Doychin N. (Συγγραφέας), Neiss, Wolfram F. (Συγγραφέας), Guntinas-Lichius, Orlando (Συγγραφέας), Streppel, Michael (Συγγραφέας), Wewetzer, Konstantin (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg, 2005.
• Σειρά: Advances in Anatomy Embryology and Cell Biology, 180
• Θέματα: Medicine.; Neurosciences.; Biomedicine.

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 Outline of the General Neurobiological Problem -- The Perikarya Which Support Axonal Regrowth are Hyperexcitable -- Axonal Regrowth is Compromised by Ephaptic Cross-Talk Between the Branches -- Biological Significance of Axonal Branching -- Role of Cytoskeleton Reorganization During Axonal Branching -- The Individual Guidance Cues Promoting Reinnervation of Original Targets are Still Unknown -- Conclusion -- Outline of the Clinical Problem -- Questions Still Open -- Methodological Approach -- Materials and Methods -- First Set of Experiments: Attempts to Reduce Collateral Axonal Branching by Alterations of the Trigeminal Input to the Facial Perikarya -- Second Set of Experiments: Attempts to Reduce Collateral Axonal Branching at the Lesion Site -- Results -- First Set of Experiments: Influence of the Altered Afferent Input to Axotomized Facial Perikarya on the Quality of Reinnervation -- Second set of Experiments: Attempts to Reduce Collateral Axonal Branching at the Lesion Site -- Discussion -- The Combined Approach to Evaluate the Quality of Peripheral Nerve Regeneration -- Sensory-Motor Integrity as A Factor for Motor Regeneration -- Collateral Branching Versus Terminal Sprouting of Axons -- Prospects for the Future -- References -- Subject index.