Free-Radical-Induced DNA Damage and Its Repair A Chemical Perspective /

• Κύριος συγγραφέας: Sonntag, Clemens von (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg, 2006.
• Θέματα: Life sciences.; Molecular biology.; Organic chemistry.; Oncology.; Biochemistry.; Cell biology.; Life Sciences.; Biochemistry, general.; Cell Biology.; Life Sciences, general.; Molecular Medicine.; Organic Chemistry.

Understanding of the molecular basis of DNA damage and its repair has increased dramatically in recent years, and substantial knowledge now exists concerning the products arising from free-radical attack on DNA. Free-radical DNA damage may lead to mutations, cancer, and cell death. Free radicals hav...

Πίνακας περιεχομένων:

• Formation of Reactive Free Radicals in an Aqueous Environment
• The Hydroxyl Radical
• Hydrogen Atom and Hydrated Electron
• Inorganic Radicals
• Carbon-Centered Radicals
• Heteroatom-Centered Radicals
• Peroxyl Radicals
• Polymer Radicals
• Nucleobases, Nucleosides and Nucleotides
• Polynucleotides and Single-Stranded DNA Fragments
• DNA and Double-Stranded Oligonucleotides
• Methods.