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03226nam a22005295i 4500 |
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20151111081422.0 |
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|a 9783540330493
|9 978-3-540-33049-3
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|a 10.1007/b97910
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|a Bioorganometallic Chemistry
|h [electronic resource] /
|c edited by Gérard Simonneaux.
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|a Berlin, Heidelberg :
|b Springer Berlin Heidelberg,
|c 2006.
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| 300 |
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|a X, 222 p.
|b online resource.
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
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|a text file
|b PDF
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|a Topics in Organometallic Chemistry,
|x 1436-6002 ;
|v 17
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|a Bernhard Kräutler: Biological Organometallic Chemistry of Vitamin B12 -- Juan C. Fontecilla-Camps: Bioorganometallic chemistry of iron-nickel clusters in enzymes -- Gérard Simonneaux: Bioorganometallic Chemistry of Metalloporphyrins -- Kay Severin: Synthetic Organometallic Hosts for Biologically Interesting Molecules -- Toshikazu Hirao: Peptide Supramolecular Systems with Metallocene derivatives -- Paul Dyson: Medicinal Properties of Organometallic Compounds.
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|a Bioorganometallic Chemistry has become a mature area of science and is comprehensively covered by leading experts in this book. Naturally occuring bioorganometallic complexes, such as vitamin B12 and recently discovered iron and nickel hydrogenases, including a possible role of the latter in the geochemical theory of the origin of life, are considered. The possible formation of carbene complexes of cytochrome P450 enzymes in various metabolisms of xenobiotics is also discussed. The bioorganometallic chemistry is considered to provide not only organometallic receptors such as polynuclear organometallic macrocycles for biologically interesting molecules but also ferrocene-peptide bioconjugates giving a peptidomimetic basis for protein folding. The medicinal properties of organometallic compounds are reviewed, with notable applications in the treatment and diagnosis of cancer and in the treatment of viral, fungal, bacterial and parasitic infections. Therefore the reader will get a balanced view of this rapidly developing and promising area.
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| 650 |
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|a Chemistry.
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| 650 |
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|a Inorganic chemistry.
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| 650 |
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|a Organometallic chemistry.
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| 650 |
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|a Medicinal chemistry.
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| 650 |
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|a Catalysis.
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| 650 |
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|a Biochemistry.
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| 650 |
1 |
4 |
|a Chemistry.
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| 650 |
2 |
4 |
|a Organometallic Chemistry.
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| 650 |
2 |
4 |
|a Inorganic Chemistry.
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| 650 |
2 |
4 |
|a Catalysis.
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| 650 |
2 |
4 |
|a Biochemistry, general.
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| 650 |
2 |
4 |
|a Medicinal Chemistry.
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| 700 |
1 |
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|a Simonneaux, Gérard.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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|t Springer eBooks
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| 776 |
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|i Printed edition:
|z 9783540330479
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| 830 |
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|a Topics in Organometallic Chemistry,
|x 1436-6002 ;
|v 17
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| 856 |
4 |
0 |
|u http://dx.doi.org/10.1007/b97910
|z Full Text via HEAL-Link
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|a ZDB-2-CMS
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| 950 |
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|a Chemistry and Materials Science (Springer-11644)
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