Analgesia

• Corporate Author: SpringerLink (Online service)
• Other Authors: Stein, Christoph (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2007.
• Series: Handbook of Experimental Pharmacology, 177
• Subjects: Medicine.; Pharmacology.; Anesthesiology.; Rheumatology.; Neurosurgery.; Surgery.; Psychology.; Biomedicine.; Pharmacology/Toxicology.; Psychology, general.

Analgesics are among the oldest drugs described, albeit not necessarily for medicinaluse. Forexample,theSumeriansisolatedopioids(probablyfortheir euphoric effects) in the third millennium b. c. and the use of willow bark (salicin) for fever was ?rst reported in the eighteenth century. Both types of...

Table of Contents:

• Peripheral and Central Mechanisms of Pain Generation
• Drugs in Clinical Use
• Opioids
• Antipyretic Analgesics: Nonsteroidal Antiinflammatory Drugs, Selective COX-2 Inhibitors, Paracetamol and Pyrazolinones
• Local Anesthetics
• Serotonin Receptor Ligands: Treatments of Acute Migraine and Cluster Headache
• Anti-convulsants and Anti-depressants
• Compounds in Preclinical Development
• Neuropeptide and Kinin Antagonists
• Glutamate Receptor Ligands
• Adrenergic and Cholinergic Compounds
• Cannabinoids and Pain
• Future Targets in Analgesia Research
• Adenosine and ATP Receptors
• Ion Channels in Analgesia Research
• Protein Kinases as Potential Targets for the Treatment of Pathological Pain
• Pain Management Beyond Pharmacotherapy
• Placebo and Endogenous Mechanisms of Analgesia
• Limitations of Pharmacotherapy: Behavioral Approaches to Chronic Pain.