Transient Receptor Potential (TRP) Channels

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Flockerzi, Veit (Επιμελητής έκδοσης), Nilius, Bernd (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg, 2007.
• Σειρά: Handbook of Experimental Pharmacology, 179
• Θέματα: Medicine.; Human physiology.; Molecular biology.; Pharmacology.; Biomedicine.; Pharmacology/Toxicology.; Human Physiology.; Molecular Medicine.

In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field have written 35 essays which describe properties of a single TRP protein/channel or portray...

Πίνακας περιεχομένων:

• An Introduction on TRP Channels
• An Introduction on TRP Channels
• TRPC Channel Subfamily
• TRPC1 Ca2+-Permeable Channels in Animal Cells
• TRPC2: Molecular Biology and Functional Importance
• TRPC3: A Multifunctional, Pore-Forming Signalling Molecule
• Ionic Channels Formed by TRPC4
• Canonical Transient Receptor Potential 5
• TRPC6
• TRPC7
• TRPV Channel Subfamily
• Capsaicin Receptor: TRPV1 A Promiscuous TRP Channel
• 2-Aminoethoxydiphenyl Borate as a Common Activator of TRPV1, TRPV2, and TRPV3 Channels
• TRPV4
• TRPV5, the Gateway to Ca2+ Homeostasis
• TRPV6
• TRPM Channel Subfamily
• TRPM2
• TRPM3
• Insights into TRPM4 Function, Regulation and Physiological Role
• TRPM5 and Taste Transduction
• TRPM6: A Janus-Like Protein
• The Mg2+ and Mg2+-Nucleotide-Regulated Channel-Kinase TRPM7
• TRPM8
• Other TRP Channels
• TRPA1
• TRPP2 Channel Regulation
• TRP Proteins and Specific Cellular Functions
• Know Thy Neighbor: A Survey of Diseases and Complex Syndromes that Map to Chromosomal Regions Encoding TRP Channels
• TRP Channels of the Pancreatic Beta Cell
• TRP Channels in Platelet Function
• TRP Channels in Lymphocytes
• Link Between TRPV Channels and Mast Cell Function
• TRPV Channels’ Role in Osmotransduction and Mechanotransduction
• Nociception and TRP Channels
• TRP Proteins — Integrators of Multiple Inputs
• Regulation of TRP Ion Channels by Phosphatidylinositol-4,5-Bisphosphate
• TRPC, cGMP-Dependent Protein Kinases and Cytosolic Ca2+
• Trafficking of TRP Channels: Determinants of Channel Function
• TRPC Channels: Interacting Proteins
• TRPC Channels: Integrators of Multiple Cellular Signals
• Phospholipase C-Coupled Receptors and Activation of TRPC Channels
• Erratum
• Erratum.