Conditional Mutagenesis: An Approach to Disease Models

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Feil, Robert (Επιμελητής έκδοσης), Metzger, Daniel (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg, 2007.
• Σειρά: Handbook of Experimental Pharmacology, 178
• Θέματα: Medicine.; Human genetics.; Molecular biology.; Pharmacology.; Medical biochemistry.; Biomedicine.; Pharmacology/Toxicology.; Molecular Medicine.; Human Genetics.; Medical Biochemistry.
• Φυσική περιγραφή: XII, 532 p. online resource.
• ISBN: 9783540351092
• ISSN: 0171-2004 ;

Leading experts provide timely and comprehensive information on methods for conditional mutagenesis in the mouse (part 1) and their application to model human physiology and pathophysiology (part 2). It illustrates how sophisticated genetic manipulations of the mouse genome are employed to model human diseases and to identify underlying molecular mechanisms. Finally the book considers the development of new drugs to treat them.