Left-Right Asymmetry in Vertebrate Development

• Main Authors: López-Gracia, Maria L. (Author), Ros, Marian (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2007.
• Series: Advances in Anatomy Embryology and Cell Biology, 188
• Subjects: Medicine.; Human physiology.; Biomedicine.; Human Physiology.

Externally the vertebrate body plan presents a bilateral symmetry in relation to the midline. However, inside the body the distribution of the visceral organs follows a very particular pattern that is not symmetrical in relation to the midline. The last 10 years have seen remarkable advances in our...

Table of Contents:

• Establishment of Left-Right Asymmetry
• Signaling Pathways with a Predominant Role in Left-Right Patterning
• Mouse Models of Laterality
• Genetics of Human Alterations of Organ Situs
• Concluding Remarks.