Organometallics in Process Chemistry

• Corporate Author: SpringerLink (Online service)
• Other Authors: Larsen, Rob (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2004.
• Edition: 1st ed. 2004.
• Series: Topics in Organometallic Chemistry, 6
• Subjects: Organometallic chemistry .; Catalysis.; Inorganic chemistry.; Medicinal chemistry.; Chemical engineering.; Organometallic Chemistry.; Inorganic Chemistry.; Medicinal Chemistry.; Industrial Chemistry/Chemical Engineering.

The design of efficient syntheses of medicinal agents is one of the prime goals of the process chemist in the pharmaceutical industry. The expanding list of metal-mediated reactions has had a major impact on this endeavor over the last two decades. This volume will highlight some of the areas of org...

Table of Contents:

• G.G. Wu, M. Huang: Organolithium in Asymmetric Processes
• D.L. Hughes: Applications of Organotitanium Reagents
• K. Sumi, H. Kumobayashi: Rhodium/Ruthenium Applications
• A.J. Delmonte, E.D. Dowdy and D.J. Watson: Development of Transition Metal-Mediated Cyclopropanation Reactions
• J.F. Larrow, E.N. Jacobsen: Asymmetric Processes Catalyzed by Chiral (Salen)Metal Complexes
• S.J. Mehrman, A.F. Abdel-Magid, C.A. Maryanoff and B.P. Medaer: Non-Salen Metal-Catalyzed Asymmetric Dihydroxylation and Asymmetric Aminohydroxylation of Alkenes. Practical Applications and Recent Advances
• M. Prashad: Palladium-Catalyzed Heck Arylations in the Synthesis of Active Pharmaceutical Ingredients
• A.O. King, N. Yasuda: Palladium-Catalyzed Cross-Coupling Reactions in the Synthesis of Pharmaceuticals
• J. Kant: Stereospecific Introduction of Cephalosporin Side Chains Employing Transition Metal Complexes
• J.T. Bien, G.C. Lane and M.R. Oberholzer: Removal of Metals from Process Streams: Methodologies and Applications.