Mathematical Methods for Protein Structure Analysis and Design Advanced Lectures /

The papers collected in this volume reproduce contributions by leading sch- arstoaninternationalschoolandworkshopwhichwasorganizedandheldwith thegoaloftakinga snapshotofadiscipline undertumultuous growth. Indeed, the area of protein folding, docking and alignment is developing in response to needs f...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Guerra, Concettina (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Istrail, Sorin (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2003.
Έκδοση:1st ed. 2003.
Σειρά:Lecture Notes in Bioinformatics ; 2666
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
LEADER 04986nam a2200601 4500
001 978-3-540-44827-3
003 DE-He213
005 20191023201648.0
007 cr nn 008mamaa
008 121227s2003 gw | s |||| 0|eng d
020 |a 9783540448273  |9 978-3-540-44827-3 
024 7 |a 10.1007/b11686  |2 doi 
040 |d GrThAP 
050 4 |a QA1-939 
072 7 |a PB  |2 bicssc 
072 7 |a MAT000000  |2 bisacsh 
072 7 |a PB  |2 thema 
082 0 4 |a 510  |2 23 
245 1 0 |a Mathematical Methods for Protein Structure Analysis and Design  |h [electronic resource] :  |b Advanced Lectures /  |c edited by Concettina Guerra, Sorin Istrail. 
250 |a 1st ed. 2003. 
264 1 |a Berlin, Heidelberg :  |b Springer Berlin Heidelberg :  |b Imprint: Springer,  |c 2003. 
300 |a XI, 157 p.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
490 1 |a Lecture Notes in Bioinformatics ;  |v 2666 
505 0 |a Protein Structure Comparison: Algorithms and Applications -- Spatial Pattern Detection in Structural Bionformatics -- Geometric Methods for Protein Structure Comparison -- Identifying Flat Regions and Slabs in Protein Structures -- OPTIMA: A New Score Function for the Detection of Remote Homologs -- A Comparison of Methods for Assessing the Structural Similarity of Proteins -- Prediction of Protein Secondary Structure at High Accuracy Using a Combination of Many Neural Networks -- Self-consistent Knowledge-Based Approach to Protein Design -- Protein Structure from Solid-State NMR -- Learning Effective Amino-Acid Interactions -- Proteinlike Properties of Simple Models. 
520 |a The papers collected in this volume reproduce contributions by leading sch- arstoaninternationalschoolandworkshopwhichwasorganizedandheldwith thegoaloftakinga snapshotofadiscipline undertumultuous growth. Indeed, the area of protein folding, docking and alignment is developing in response to needs for a mix of heterogeneous expertise spanning biology, chemistry, mathematics, computer science, and statistics, among others. Some of the problems encountered in this area are not only important for the scienti?c challenges they pose, but also for the opportunities they disclose intermsofmedicalandindustrialexploitation. Atypicalexampleiso?eredby protein-drug interaction (docking), a problem posing daunting computational problems at the crossroads of geometry, physics and chemistry, and, at the same time, a problem with unimaginable implications for the pharmacopoeia of the future. The schoolfocused on problems posed by the study of the mechanisms - hind protein folding, and explored di?erent ways of attacking these problems under objective evaluations of the methods. Together with a relatively small core of consolidated knowledge and tools, important re?ections were brought to this e?ort by studies in a multitude of directions and approaches. It is obviously impossible to predict which, if any, among these techniques will prove completely successful, but it is precisely the implicit dialectic among them that best conveys the current ?avor of the ?eld. Such unique diversity and richness inspired the format of the meeting, and also explains the slight departure of the present volume from the typical format in this series: the exposition of the current sediment is complemented here by a selection of quali?ed specialized contributions. 
650 0 |a Mathematics. 
650 0 |a Algorithms. 
650 0 |a Computer science-Mathematics. 
650 0 |a Database management. 
650 0 |a Computer graphics. 
650 0 |a Optical data processing. 
650 1 4 |a Mathematics, general.  |0 http://scigraph.springernature.com/things/product-market-codes/M00009 
650 2 4 |a Algorithm Analysis and Problem Complexity.  |0 http://scigraph.springernature.com/things/product-market-codes/I16021 
650 2 4 |a Discrete Mathematics in Computer Science.  |0 http://scigraph.springernature.com/things/product-market-codes/I17028 
650 2 4 |a Database Management.  |0 http://scigraph.springernature.com/things/product-market-codes/I18024 
650 2 4 |a Computer Graphics.  |0 http://scigraph.springernature.com/things/product-market-codes/I22013 
650 2 4 |a Image Processing and Computer Vision.  |0 http://scigraph.springernature.com/things/product-market-codes/I22021 
700 1 |a Guerra, Concettina.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
700 1 |a Istrail, Sorin.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
776 0 8 |i Printed edition:  |z 9783540401049 
776 0 8 |i Printed edition:  |z 9783662192887 
830 0 |a Lecture Notes in Bioinformatics ;  |v 2666 
856 4 0 |u https://doi.org/10.1007/b11686  |z Full Text via HEAL-Link 
912 |a ZDB-2-SCS 
912 |a ZDB-2-LNC 
912 |a ZDB-2-BAE 
950 |a Computer Science (Springer-11645)